This increases the regenerative capacity (self-healing capacity) of the liver. The root of this plant can also be eaten; you can prepare milk thistle roots in the same way as salsify. To reduce menopausal symptoms, milk thistle was combined with black cohosh, dong quai, red clover, American ginseng, and chaste-tree berry . Plus dosage, safety, side effects, drug interactions and more. Milk thistle is generally considered safe and well-tolerated, with very few cases of side effects reported. People with diabetes should use caution. Milk thistle raises the blood pressure to healthy levels. Not Advisable for People Suffering from Liver Disorders: It is not suggested to be administered to … Milk thistle sometimes causes a laxative effect. The following two tabs change content below. Chlorpromazine, Haloperidol, Promethazine or Flufenazine). However, it is primarily known for protecting your liver against alcohol, pollutants and other toxins, helping to regenerate healthy liver cells and improve your overall liver function. Diabetes/ Anti-diabetic Medications- caution. Healthy adults should limit their milk thistle dosage to 280 to 450 millgrams a day. How long does it take for milk thistle to start working? Sunflower Oil Vs. Olive Oil - Which Is Better? StyleCraze believes in credibility and giving our readers access to authentic and evidence-based content. Since the active nutrients in the seed are very poorly soluble in water, making milk thistle tea is not such a good idea. The most common side effects aren’t serious and include gastrointestinal upset, such as a mild laxative effect. Milk thistle has been shown to have both anti-oxidant and anti-inflammatory properties. Can Interact With Estrogen 4. Milk Thistle’s Positive Estrogenic Effects. 13 years experience Infectious Disease. Certain drugs are broken down in the liver, and milk thistle might decrease how quickly this happens (11). Hence, stay safe and avoid use. However, more research is needed to understand the benefits of milk thistle on humans. Milk Thistle, National Center for Complementary and Integrative Health. Individuals using milk thistle have reported abdominal problems, allergic reactions, and interactions with estrogen and certain types of medications. The portal vein sends oxygen-poor, nutrient-rich blood to the intestines, stomach, spleen and liver. If side effects do happen, the most common ones are nausea, bloating or stomach discomfort. Milk Thistle is a popular herbal remedy that may be beneficial for those who overindulge in alcohol. Supplements containing extracts of the silymarin-phosphatidylcholine compound are generally limited to 200 to 400 milligrams a day, while herbal tinctures and liquid extracts of milk thistle often include recommended dosages on their labels according to the level of dilution. Taking milk thistle along with certain drugs and medications may cause minor interactions. He graduated from SRM University, Chennai, and has been in the digital media field for over six years. Milk thistle has been shown to have both anti-oxidant and anti-inflammatory properties. We avoid using tertiary references. The silymarin found in milk thistle can increase the bile solubility, which … Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Occasionally, people report various digestive side effects. Although no research has been done into this interaction, it is assumed in the medical world that the following medications in combination with milk thistle can cause undesirable reactions and side effects: Anxiolytics (e.g. In men, the testes are responsible for testosterone production. Ifyou have allergies to ragweed, marigolds, chrysanthemums, daisies,artichokes or kiwi, there is a risk that you will get an allergicreaction to milk thistle as well. High doses of the herb can cause elevated levels of bilirubin and liver enzymes. Might Cause Abdominal Issues 2. Investigating the Potential for Toxicity From Long-Term Use of the Herbal Products, Goldenseal and Milk Thistle, Toxicologic Pathology, US National Library of Medicine, National Institutes of Health. Are They Good For You? Silymarin will optimize protein synthesis and promote the production of RNA, thus creating more new liver cells. Taken in appropriate doses, oral use of milk thistle appears to be safe.Milk thistle can cause: 1. Lonicerus, an important German doctor, wrote in a herbal book around 1550 that the milk thistle works well against liver diseases. These can include hives, a rash, and difficulty breathing. Milk thistle has a strong antioxidant effect, prevents lipid peroxidation, promotes detoxification through increased glucorindation, reduces the activity of certain toxic enzymes, stabilizes liver cell membranes, stimulates regeneration of the liver after toxin damage, reduces liver inflammation and increases glutathione levels, the body's own antioxidant. In some cases the user may suffer from stomach discomfort, whether or not in combination with diarrhea. Occasionally, people report various digestive side effects. Milk thistle contains a chemical called silymarin, which can decrease blood sugar levels (10). All medicinal effects of this herb mentioned in the article are based on scientific research and are taken from the Great Manual of Medicinal Plants by Geert Verhelst, a standard work in the field of healing plants. Milk thistle, like many natural products, has few or no side effects. Milk thistle side effects are uncommon but can range from mild to quite severe. Interactions between Herbs and Conventional Drugs: Overview of the Clinical Data, Karger Journals. Milk thistle has the miraculous property of allowing toxins to pass through the liver without causing damage. Milk thistle is used as a medicine when an unfamiliar person eats poisonous mushrooms such as Amanita Phalloides (Death cap). There can also be undesirable side effects if milk thistle is taken in combination with regular medication. Based on clinical trial data, a safe dosage is 420 milligrams per day of oral milk thistle containing 70 to 80 percent silymarin in divided doses for up to 41 months. This article has been reviewed and fact-checked by doctors and other experts from the medical fraternity. Others may include headaches, mild diarrhea, joint pain, skin allergies, rash, loss of appetite, nasal congestion and insomnia . Milk thistle interacts with these drugs as both are broken down by the same liver enzymes. Might Interact With Other Drugs 8. The book is widely used in phytotherapy. Because of these medicinal properties, phytotherapists can prescribe milk thistle: The portal circulation is the blood circulation from the intestines to the liver. The people who gave names to organs knew how important the liver is; literally the meaning of liver is: donor of life. Supports liver health. In women, the ovaries and the adrenal glands both produce testosterone, according to the website Aphrodite Women’s Health. John Evelyn wrote that if the plant was stripped of its spines it was an excellent wild vegetable that is especially recommended for nursing mothers. The active constituents of milk thistle supplements are believed to be the flavonolignans contained within the extracts. While it could also cause drug interactions, research is mixed. Milk thistle is commonly used as a home remedy to treat liver problems, often under the presumption that it will "detoxify" the liver. A phytotherapist can tell you more about this as well as about possible side effects and interactions with other medicines or herbs. The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. nausea, loss of appetite. Side effects include stomach upset, allergic reaction, and diarrhea. He recommended carrot for coughing, mixed with honey. “Silymarin”, a Promising Pharmacological Agent for Treatment of Diseases, Iranian University of Medical Sciences, US National Library of Medicine, National Institutes of Health. Less commonly, muscle aches, joint pain, and sexual dysfunction have been reported. If you want to use milk thistle as a medicine, you are advised to consult a phytotherapist. Can Interact With Cholesterol Medication 5. Prickly yet pretty, milk thistle is a plant with a long, thin stem, spiny leaves, and a purplish-pink thistle at the top. There are a lot of things you can do first to reduce your symptoms. The cannabinoids in CBD oil interact with the endocannabinoid system in the body and can cause various effects. Gallbladder and Gallstones. The most important contents are the flavanolignans. Click here for additional information . This does not apply if you have a known allergic reaction to other plants that are related to the milk thistle plant. The effects of plant compounds often referred to as “phytoestrogens” like those in in ground flaxseeds, nuts and seeds, soy, many fruit and medicinal plants on estrogen receptors and metabolism is quite complex. In severe cases, the liver is affected to such an extent that the victim dies; you cannot live without it. One of the most common uses of milk thistle is to treat liver problems. However, it is primarily known for protecting your liver against alcohol, pollutants and other toxins, helping to regenerate healthy liver cells and improve your overall liver function. Might Cause Abdominal Issues 2. Pregnant and breast-feeding women should avoid the herb.Adverse side effects are usually mild. The aforementioned medicinal properties are the primary activities for which phytotherapists use milk thistle. Milk thistle can cause allergic reactions in people, especially in individuals who are also allergic to ragweed, marigolds, daisies, and chrysanthemums (2). May Interact With Cholesterol Medication. There is also concern that milk thistle might have estrogenic effects. Milk thistle may produce allergic reactions, which tend to be more common among people who are allergic to plants in the same family (for example, ragweed, chrysanthemum, marigold, and daisy). Dioscorides was the first to describe the medicinal effects of milk thistle. Further research is needed but applying some milk thistle topically to the skin could be the key to a clear and healthy skin. In the Middle Ages, Greek and Roman knowledge about milk thistle spread to the rest of Europe. As a food supplement you will often find milk thistle in combination with other nutrients or plants such as the dandelion. The Silymarin has a very strong and positive effect on your liver in two ways: Silymarin is capable of altering the external layer of the liver cells, so that any toxic substances that may be present can no longer penetrate the liver cells. Do Purple Potatoes Grow Naturally? Normally you should be able to notice the positive effects within a few weeks, although in case of chronic diseases it can take a bit longer. Milk thistle is an herbal supplement that is claimed to have numerous health benefits. Milk Thistle Protects Your Liver. If you are taking this herb/supplement, you should be wary of the possible adverse effects it can cause. Milk thistle Scientific classification Kingdom: Plantae Clade: Tracheophytes Clade: Angiosperms Clade: Eudicots Clade: Asterids Order: Asterales Family: Asteraceae Genus: Silybum Species: S. marianum Binomial name Silybum marianum Gaertn. Side-effects aren’t common but include:11,12 1. itchiness 2. headaches 3. diarrhoea 4. nausea Allergic reactions, including anaphylaxis, are rare but have been reported. There are very few known side effects of milk thistle so you probably don't have to worry about milk thistle dangers if you take recommended dosages. Review of Clinical Trials Evaluating Safety and Efficacy of Milk Thistle (Silybum marianum [L.] Gaertn. Can Have Interactions During Breastfeeding And Pregnancy 7. In 1954 it was discovered that silymarin, a collective name for a flavonoid mixture, is the most important active factor of milk thistle. Yes, you can drink alcohol while taking milk thistle. Share on Pinterest. He started his career as a research writer, primarily focusing on health and wellness, and has over 250 articles to his credit. It also contains the sterols cholesterol, campesterol, stigmasterol and sitosterol. Milk thistle is often promoted for its liver … The term 'lipotropic factors' is also often used. Milk Thistle Dosage. Very few people experience serious side effects of taking milk thistle. 4. Food poisoning. You might also get the herb at your nearest supermarket/pharmacy. Other less common side effects are nausea, diarrhea, indigestion, intestinal gas, bloating, fullness or pain, and loss of appetite. Thissupplement is shown to lower bloodsugar levels in animals. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Especially with jaundice, milk thistle was the most important medicine at that time. In the most severe cas… Though milk thistle has been historically used to improve the flow of breast milk, its benefits during breastfeeding and pregnancy are not well studied yet. StyleCraze provides content of general nature that is designed for informational purposes only. Other substances that are in it to a lesser extent are: dehydrodiconiferyl alcohol, protein, amino acids, betaine, unsaturated fatty acids such as linoleic acid, oleic acid and palmitic acid, bitter substances, catechol tanning substances, essential oil, sugars, mucilages, polyins and bitter resin acids. However, if you develop an allergic reaction after taking milk thistle, stop use and consult your doctor. This herb has been around since Greco-Roman times. Some dogs may experience loose feces or gas, and it may also suppress liver function if given too often. In animal studies, the antioxidant and radical-scavenging properties of silibinin in milk thistle were found to reduce tumors (16). 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